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HFE Gene Linked to MN
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Protein Linked to Kidney Failure
arrowNIH Renews NEPTUNE Funding
Childhood Stress not trigger for MS
arrowLevin succeeds Remuzzi at ISN

arrowSalant receives Hamburger Award
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arrowA Cause of Recurrent MN
arrowBlood Test Detects Kidney Rejection
Genotyping of Risk Alleles
arrowLink to Gene Variants
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arrowKey Molecule Impacts Mice
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Variations in HLA-DQA1 & PLA2R1
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arrowLink between MN and Milk (NEJM)

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Advisors on Grant Selection

William Couser, MD
Dr. Couser was educated at Harvard University Medical School. He is a medical researcher, educator, clinical nephrologist, medical journal editor and leader in the field.

As a medical researcher, he directed laboratory research on immunologic kidney disease with continuous funding from US NIH from 1972-2004. He is a NIH MERIT Award recipient. Dr. Coiuser was Director of George M O'Brien Kidney Research Center at the University of Washington (1992-2002) and contributed to more than 300 publications on immune renal diseases.

As a medical educator, he trained over 60 clinical nephrologists and over 30 basic investigators from 6 countries as Belding H. Scribner Professor of Medicine and Head of the Division of Nephrology at the University of Washington in Seattle, WA (1982-2004).

Dr. Couser is board certified in internal medicine and nephrology and provided patient care from 1972-2004 at Universities of Chicago, Boston University and University of Washington specializing in glomerular diseases. He was named one of nine nephrologists listed in Americas Top Physicians by American Health magazine and listed in the Guide to America's Top Physicians published by the Consumer Research Council of America.

He served as Editor-in-Chief of the Journal of the American Society of Nephrology (JASN), the top-ranked journal in the kidney-urology field, from 2001-2007 and was President of the American Society of Nephrology (1995-96), inaugural president of the Council of American Kidney Societies (1996-97) and president of the International Society of Nephrology (2005-07).

Dr. Couser is currently chairperson of the International Society of Nephrology Global Outreach Programs (ISN-GO) for advancing nephrology in the developing world.

Ronald Falk, MD
Dr. Falk's research probes questions focused on immune mediated kidney diseases, especially glomerulonephritis. His clinical and basic science interests include both ANCA glomerulonephritis and small vessel vasculitis (SVV). A central objective of Dr. Falk's research is elucidating the causes of ANCA necrotizing and crescentic glomerulonephritis. Unraveling the cause of this disease requires considering a number of factors involved in the development of ANCA glomerulonephritis. Dr. Falk conceptualizes this process as opening the vasculitis lock with a key that has a number of "ridges and valleys" analogous to those factors that contribute to the development of this autoimmune disease. He participates in a research group that, in a large study over the last four years has revealed a number of avenues of investigation and new approaches to ongoing questions that pertain not only to ANCA glomerulonephritis, but to the general fields of autoimmunity, inflammation and basic neutrophil and monocyte biology.

Ilya Hulinsky, MD, PhD.
Dr. Hulinky's research focuses on Clinical Endocrinology, with an emphasis on Islet physiology, transplantation, growth and regeneration and well as immunology. Journal articles include "Insulin Secretion and DNA Synthesis of Cultured Islets of Langerhans is influenced by Matrix," Pancreas, 1995 (with Harrington J., Cooney S., and Silink M.); and "Alterations in Parameters of Cellular Immunology in Type 1," Diabetes.

Awards of note: The R.L. Cooper Foundation research awards in 1991, 1992 and 1994, including Leo Dientenfass Prize for 'Most Interesting Research Project' in 1991; Distinction of the Dean for 'Outstanding Academic Performance' presented by the Dean, Faculty of Medicine, Charles' University. Upon graduation in 1985; and Prize of the Dean for 'Best Student of the Year' presented by the Dean, Faculty of Medicine, Charles' University in 1981;

He received his M.D. from Charles' University, Prague in 1985 and PhD in 1989 from Academy of Sciences of the Czech Republic, PhD. His postgraduate degrees include Diplomate in Endocrinology, Diabetes, and Metabolism, Certification Examination, American Board of Internal Medicine, USA; Diplomate in Internal Medicine, Certification Examination in Internal Medicine, American Board of Internal Medicine, USA; Specialist Physician Diploma in Internal Medicine (Grade II); and Institute of Postgraduate Medical Education, Prague, Czech Republic. Hospital affiliations include Griffin Hospital and Bridgeport Hospital (both of Yale New Haven Health), Hospital of St. Raphael and St. Vincent's Medical Center, all in Connecticut.

Robert Kleta, MD, PhD, FASN, FACMG
Professor Kleta is Potter Chair of Nephrology at the University College London (UCL) and teaches at the Royal Free Hospital / Medical School in the United Kingdom. He is also a member of the Department of Medicine, Department of Physiology and the UCL Genetics Institute, Institute of Child Health. The Genetics Institute was established to create a world-leading centre to develop and apply biostatistical and bio-informatics approaches to genetic research. Its major, although not exclusive, mission is to focus on clinical and human population genetics. This will form a platform from which UCL can address major challenges to the use of genetics in healthcare.

He also is a member of the Great Ormond Street Hospital for Children NHS Trust and Royal Free Hampstead NHS Trust.

Pierre Ronco, MD, PhD
Dr. Ronco graduated from the University Pierre et Marie Curie (UPMC, Paris, France) where he was appointed in 1986 as a Professor of Renal Medicine. He became chief of the renal division at Tenon hospital in 1995 and of the INSERM Unit 489/702 in 1998.

His main fields of interest are renal immunopathology, and genetics, and the mechanisms of kidney repair. He wrote over 300 articles in peer-reviewed journals, book chapters and monographs. He received several national and international prizes including the Jean Hamburger Award (1999, City of Paris); Marguerite Delahautemaison Award (2000, French Foundation for Medical Research); the Jean Valade Award (2005, Fondation de France); and the 2007 ISN Jean Hamburger Award, for his contribution to clinical and translational nephrology in the area of pathomechanisms of glomerular disease. He is a member of the French Academy of Medicine, the Royal Academy of Medicine (Belgium), and the Institut Universitaire de France.

He has been a member of American Society of Nephrology Programme Committee for the 2008 Annual Meeting (Philadelphia) and a co-chair of the Scientific Programme Committee of the World Congress of Nephrology in Milan 2009. He is currently serving as the President of the ERA-EDTA meeting in Paris, 2012.

He trained over 50 PhD and postdoc fellows in the past 20 years and received a special award for excellence in teaching from UPMC University.

David J. Salant, MD
Dr. Salant is Chief of the Renal Section and Professor of Medicine at Boston University. He obtained his medical degree from the University of the Witwatersrand in Johannesburg, South Africa and joined the full-time faculty at Boston University after completing research training with Dr. William G. Couser at Boston University. Prior to that he was a member of the Renal Section at the Johannesburg General Hospital in South Africa where he gained extensive experience in renal transplantation, dialysis and other aspects of clinical nephrology.

Dr. Salant is a senior investigator whose research is supported by grants from the National Institutes of Health. His research into the mechanisms of glomerular injury is of considerable topical interest and has received national and international recognition. His work has been regularly presented at scientific sessions of the American Society of Nephrology and other scientific meetings. He has further contributed to the proceedings of these organizations by reviewing abstracts, chairing scientific sessions and symposia, and delivering invited lectures. He also served for several years as a member of a NIH Study Section.

In addition to more than 130 contributions to the scientific literature, Dr. Salant has written several clinical papers on diverse nephrological subjects and book chapters on glomerular diseases and vasculitis of the kidney. He was an author of MKSAP IX and chairman of the ABIM Subspecialty Board of Examiners in Nephrology. NEWS: Dr. Salant wins ASN Jean Hamburger Award >

Stuart Evan Seropian, MD

Dr. Seropian graduated from George Washington University Medical School and served as a fellow at Yale University School of Medicine. He also completed a residency at Yale-New Haven Hospital before becoming Associate Professor of Medicine at Yale. He specializes in Hematology and Oncology. His clinical interests range from Hodgkin's disease, Non-Hodgkin's Lymphoma (NHL), multiple myeloma, bone marrow transplant and stem cell transplantation.